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Prothiaden 25/75mg, Dosulepin Uses and Side Effects

Prothiaden for Anxiety

Prothiaden is produced by Abbot, it contains Dosulepin Hydrochloride. It is being used for the indication and treatment of depressive illness, anxiety, tension, and migraine headache, etc. Dosulepin is only being used in patients intolerant to other anxiety medicines such as bromazepam and alprazolam. Prothiaden contains anxiolytic properties. It is antidepressant and anxiolytic medicine; therefore it should be consumed on advice.

Symptoms of Anxiety

PhysicalPsychologicalBehavioral
Shortness of breathExcessive worryobsessive
Heart poundingIrritability phobic
DizzinessFatigueAvoidance of situations
HeadacheVivid dreamsDistress in social situations
RestlessnessDecreased memoryFatigue

Side Effects

Blood and lymphatic system disorder: It can cause bone marrow depression and agranulocytosis.

General disorders and administration site conditions: In general disorder, it can cause asthenia

Immune system disorder: Dosulepin hydrochloride can affect the immune system as well, it can cause hypersensitivity reactions

Endocrine disorder: In some cases, it also causes inappropriate antidiuretic hormone (ADH) secretion, endocrine side effects, etc.

Metabolic and nutrition disorder: It metabolic and nutrition Prothiaden can cause hyponatremia

Psychiatric disorders: Mania and paranoid delusions, suicidal ideation, and headache

Reproductive system and breast disorder: Interference with sexual function may occur.

Skin and subcutaneous tissue disorders: Prothiaden also cause skin rashes and sweating

Hepatobiliary Disorder: It also causes hepatitis (including altered liver function), cholestatic jaundice.

Cardiac and vascular disorders: Hypotension and cardiac arrhythmias are likely to occur with high dosage.

Overdosage

Death may occur from overdosing on Dosulepin Hydrochloride. Therefore do not use Prothiaden with alcohol. Toxicity may occur within 4-5 hours after oral administration.

Symptoms of overdose include excitement, dry mouth, unconsciousness, drowsiness, visual hallucinations, urinary retention, and depression, etc. Those patients who have taken >5mg/kg should seek immediate medical attention.

Contraindications

Dosulepin is contraindicated in patients with recent myocardial infarction and degree of heart block

It is also contraindicated for the treatment of mania

Dosulepin is contraindicated for patients with severe liver disease

And also those patients who are hypersensitive to Dosulepin Hydrochloride

Pregnancy and Lactation

Do not use Dosulepin during pregnancy and lactation. Dosulepin is excreted in human milk; therefore do not use Prothiaden in pregnancy and lactation. Do not breastfeed while taking Prothiaden.

Prothiaden 25mg Tablets

Prothiaden 25mg TabletsDosulepin Hydrochloride
CompositionEach film coated contains Dosulepin Hydrochloride BP 25mg
Symptoms and IndicationsDepression, Anxiety, Nerviness, Migraine Headache, Confusion
DosageAccording to advice
CompanyAbbott
Per tablet priceRs 1.47

Prothiaden 75mg Tablets

Prothiaden 75mg TabletsDosulepin Hydrochloride
CompositionEach film coated contains Dosulepin Hydrochloride BP 75mg
Symptoms and IndicationsDepression, Anxiety, Nerviness, Migraine Headache, Confusion
DosageAccording to advice
CompanyAbbott
Per tablet priceRs 3.1

 

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