Prothiaden is produced by Abbot, it contains Dosulepin Hydrochloride. It is being used for the indication and treatment of depressive illness, anxiety, tension, and migraine headache, etc. Dosulepin is only being used in patients intolerant to other anxiety medicines such as bromazepam and alprazolam. Prothiaden contains anxiolytic properties. It is antidepressant and anxiolytic medicine; therefore it should be consumed on advice.
Symptoms of Anxiety
Physical Psychological Behavioral
Shortness of breath Excessive worry obsessive
Heart pounding Irritability phobic
Dizziness Fatigue Avoidance of situations
Headache Vivid dreams Distress in social situations
Restlessness Decreased memory Fatigue
Side Effects
Blood and lymphatic system disorder: It can cause bone marrow depression and agranulocytosis.
General disorders and administration site conditions: In general disorder, it can cause asthenia
Immune system disorder: Dosulepin hydrochloride can affect the immune system as well, it can cause hypersensitivity reactions
Endocrine disorder: In some cases, it also causes inappropriate antidiuretic hormone (ADH) secretion, endocrine side effects, etc.
Metabolic and nutrition disorder: It metabolic and nutrition Prothiaden can cause hyponatremia
Psychiatric disorders: Mania and paranoid delusions, suicidal ideation, and headache
Reproductive system and breast disorder: Interference with sexual function may occur.
Skin and subcutaneous tissue disorders: Prothiaden also cause skin rashes and sweating
Hepatobiliary Disorder: It also causes hepatitis (including altered liver function), cholestatic jaundice.
Cardiac and vascular disorders: Hypotension and cardiac arrhythmias are likely to occur with high dosage.
Overdosage
Death may occur from overdosing on Dosulepin Hydrochloride. Therefore do not use Prothiaden with alcohol. Toxicity may occur within 4-5 hours after oral administration.
Symptoms of overdose include excitement, dry mouth, unconsciousness, drowsiness, visual hallucinations, urinary retention, and depression, etc. Those patients who have taken >5mg/kg should seek immediate medical attention.
Contraindications
Dosulepin is contraindicated in patients with recent myocardial infarction and degree of heart block
It is also contraindicated for the treatment of mania
Dosulepin is contraindicated for patients with severe liver disease
And also those patients who are hypersensitive to Dosulepin Hydrochloride
Pregnancy and Lactation
Do not use Dosulepin during pregnancy and lactation. Dosulepin is excreted in human milk; therefore do not use Prothiaden in pregnancy and lactation. Do not breastfeed while taking Prothiaden.
Prothiaden 25mg Tablets
Prothiaden 25mg Tablets Dosulepin Hydrochloride
Composition Each film coated contains Dosulepin Hydrochloride BP 25mg
Symptoms and Indications Depression, Anxiety, Nerviness, Migraine Headache, Confusion
Dosage According to advice
Company Abbott
Per tablet price Rs 1.47
Prothiaden 75mg Tablets
Prothiaden 75mg Tablets Dosulepin Hydrochloride
Composition Each film coated contains Dosulepin Hydrochloride BP 75mg
Symptoms and Indications Depression, Anxiety, Nerviness, Migraine Headache, Confusion
Dosage According to advice
Company Abbott
Per tablet price Rs 3.1