What Are the Long-Term Side Effects of Losartan?

Long-Term Side Effects of Losartan

Losartan is a medication that blocks angiotensin II, a protein that narrows blood vessels and increases fluid in the body. This medication reduces the work of the heart and blood pressure and has a protective effect on the kidneys. Although side effects are rare, they can occur. Diarrhea, dizziness, cough, and weakness can occur. Losartan can also cause kidney damage.


A study published in JAMA Internal Medicine has linked a blood pressure medication called losartan with diarrhea. The cause of this side effect is unknown. Losartan is an angiotensin receptor blocker. Diarrhea is a common side effect of these medications, but it can also be caused by other conditions. One example of diarrhea caused by losartan is celiac disease. This type of bowel disorder can be fatal.


Losartan is a common blood pressure medication. It can cause a wide range of side effects. In a small percentage of cases, the drug can cause severe kidney damage. Other possible long-term side effects of losartan include slowed heart rate, low blood pressure, and swelling of the face, lips, tongue, or throat. Losartan can also cause dizziness or faintness; some people may experience worsening existing kidney conditions. It is also known to cause unexplained weight gain and swelling of the feet.


Losartan potassium is a prescription medication that lowers blood pressure in people with hypertension. High blood pressure is harmful, as it can damage the kidneys and increase the risk of stroke. Low blood pressure is also dangerous, as it can lead to dizziness, fainting, blurred vision, and fatigue. The main side effects of losartan are dizziness and low blood pressure.


Cough is one of the long-term side effects of losartan, a nitrate that belongs to the angiotensin receptor blocker (ARB) class. Cough is a common side effect of an ACE inhibitor, but it is not familiar with losartan. Patients who experienced a cough while using an ACE inhibitor should tell their doctor about their experience with losartan. They should discuss the risk of cough with their doctor, especially if they have a history of kidney or liver disease. If they are pregnant or nursing, they should also inform their physician.

High Blood Potassium (Hyperkalemia)

A new study suggests that high blood potassium (hyperkalemia) may be a side effect of losartan. This adverse event is often associated with b-blockers, which are antihypertensive drugs. This study examined the use of ACEIs and ARBs in patients with hypertension and found that hyperkalemia was associated with patients using a combination of these two drugs.

Skin Rash

Losartan is a blood pressure medication that can cause skin rash in some patients. Although this is rare, it should be reported to your doctor if you notice any of these side effects. This medication may interact with other medicines, such as aspirin and other NSAIDs. Also, it may interact with vitamins and herbal products. Make a list of all your medications so your doctor can review them. You should also document the date you started taking each type of medicine and any of its side effects.

Dry Mouth

One of the most common side effects of ACE inhibitors, which are used to treat high blood pressure, is dry mouth. People taking these medications are at risk for dry mouth, but there are ways to manage the condition. First, people with dry mouths should contact their doctor. A change in medication might help. Patients should also avoid discontinuing any medication that they’re taking for this condition if they have other health problems.