Cefim (Cefixime) Indications, Dosage and Side Effects

Cefim is a semi-synthetic third-generation cephalosporin antibiotic, which is being used to treat gram-positive and gram-negative bacteria and a wide variety of bacterial infections. Cefixime is being used to treat Typhoid, Otitis Media, UTI, Abscess, Tonsillitis, Diarrhea, Bronchitis and also being given after surgical processors in order to control the infection.

Gram-Positive Organism includes Streptococcus Pneumonia, Streptococcus Pyogense, and Streptococcus agalactiae.

Gram-Negative organism includes Haemophilus Influenza, Moraxella, Escherichia Coli, Neisseria Gonorrhea, Proteus Mirabilis, Klebsiella Pneumonia, Providencia Species, Citrobacter diversus, and Proteus mirabilis, etc.

Cefim came in four different prescription forms, Cefim 100mg and 200mg Suspension and Cefim 200mg and 400mg Capsules.

According to ncbi.nlm.nih.gov, Cefixime is also the best medicine to treat group A and B streptococci and streptococcus Pneumonia. Secondly, it is also compatible with Cefaclor and Amoxicillin in order to treat Otitis media in children.  

It is the best medicine to treat Typhoid. Typhoid is an infection caused by the bacterium Salmonella Typhimurium (S.typhi). This microorganism lives in the bloodstream and in the intestines of the human body. S.typhi is a microorganism that enters through the mouth and spends some days in the intestines, from that it directly enters the bloodstream and from that, it enters into the tissues and other organs. You can detect the presence of S.typhi via blood and urine test in the laboratory. If you get a positive result in a case, you need to take Cefixime in order to get rid of that microorganism.

Indications

Upper respiratory tract infection (URTI) e.g Sinusitis, Otitis Media, Tonsillitis, and pharyngitis

Lower respiratory tract infection (LRTI) e.g Urinary tract infection (UTI), Bronchitis,

Typhoid

Diarrhea

Pneumonia

Skin and Soft tissue infection

Abscess

Post-operation and surgical processors  

Cefim has shown to be active against most strains of the following Gram-Positive and Gram-Negative Microorganisms.

Dosage and Administration

Dosage for children

Cefim 100mg Suspension Dosage

AgeDosage
1-4 Years5ml daily
5-9 Years10ml daily
10-12 Years15ml daily

Cefim 200mg DS Suspension Dosage

AgeDosage
1-4 Years2.5ml daily
5-9 Years5ml daily
10-12 Years7.5ml daily
Above 12 years10ml daily

Dosage for Adults

Cefim 200mg and 400mg Capsules 

Before giving dosage to adults renal function should be assessed with its dosage.  

AgeDosage
12-18 Years200mg Capsule onces daily
Above 18400mg Capsule onces daily

Side Effects of Cefim

Cefixime is generally well tolerated but sometimes adverse reactions occur and also they were mild to moderate.

Gastrointestinal Disturbance: The most common side effect of Cefim is diarrhea and stool changes. Do not use Cefim if you face severe or marked diarrhea. In the gastrointestinal, it also causes nausea, dyspepsia, vomiting, abdominal pain, and flatulence, etc.

Hypersensitivity Reactions: You may find these symptoms and allergies while taking Cefixime, such as rash, drug fever, pruritis, and pruritus.

Central Nervous System: Cefixime also causes headache, dizziness, and confusion in some cases.

Hematological and Clinical Chemistry: It also causes thrombocytopenia, eosinophilia, and leukopenia in some cases.

Precautions/Warning

Do not give Cefim to those patients who are hypersensitive to Cephalosporin antibiotics. It should be given to penicillin-sensitive patients. Consult your physician if you have kidney transplantation or you have any surgical procedure recently.

Pregnancy and Lactation

Studies in mice and rats have shown evidence of impaired fertility or harm to the fetus due to the use of Cefixime 400mg. There is no adequate and well research performed on Cefixime in pregnancy and lactation, therefore consult your physician before taking Cefixime in pregnancy and lactation. Cefixime is safer in lactation than pregnancy. In pregnancy, it harms the fetus.

Cefim Suspension for Children

Cefim 100mg Suspension 30ml

Cefim 100mg Suspension

Cefim 100mg SuspensionCefixime
CompositionsEach 5ml contains Cefixime U.S.P 100mg
Symptoms and IndicationsDiarrhea, Fever, Body Ache, Pneumonia, High Temperature, Infection, Typhoid
DosageAccording to above table
CompanyHelton Pharma Ltd
Retail priceRs165

Cefim DS 200mg Suspension 30ml

Cefim DS 200mg Suspension

Cefim DS 200mg SuspensionCefixime
CompositionsEach 5ml contains Cefixime U.S.P 200mg
Symptoms and IndicationsDiarrhea, Fever, Body Ache, Pneumonia, High Temperature, Infection, Typhoid
DosageAccording to above table
CompanyHelton Pharma Ltd
Retail priceRs260

Cefim Capsules for Adults 

Cefim 200mg Capsules

Cefim 200mg Capsules

Cefim 200mg CapsulesCefixime
CompositionsEach capsule contains Cefixime U.S.P 200mg
Symptoms and IndicationsDiarrhea, Fever, Body Ache, Pneumonia, High Temperature, Infection
DosageAccording to above table
CompanyHelton Pharma Ltd
Per tablet priceRs 40

Cefim 400mg Capsules

Cefim 400mg Capsules

Cefim 400mg CapsuelsCefixime
CompositionsEach capsule contains Cefixime U.S.P 400mg
Symptoms and IndicationsDiarrhea, Fever, Body Ache, Pneumonia, High Temperature, Infection, Typhoid
DosageAccording to above table
CompanyHelton Pharma Ltd
Per tablet priceRs 69